Protein or peptide name: | pDelta-1 |
Chromosome: | Hepatitis delta virus (HDV) RNA genome |
Protein or peptide start site: | 63 |
Protein or peptide end site: | 359 |
ncRNA start site: | 63 |
ncRNA end site: | 359 |
Genome Browser: | NA |
Protein or peptide sequence: | PLLSLLSSSLASPPTPSHSSTATGLTPTAASASNSLKGSSGGDKSAHLAVDSSLTVLLAPSGASALQHTALGPSDAQAASKKKHLPLSPSADSPALTGSAPLPQTSLNKLGVVSPTKQNSLP |
Protein or peptide length: | 122aa |
ncRNA type: | circRNA |
ncRNA name: | pDelta-1 |
Entrez ID: | NA |
Experimental species: | Hepatitis delta virus |
Experimental techniques: | Electron micrographs/Northern blot hybridization |
Experimental sample (cell line and/or tissue): | HDV |
Description: | Only one open reading frame gave a stretch of appreciable length (122 amino acids) with a stop codon (TGA)70 bp before the end of the cDNA at nucleotide 370 .It contains three hydrophobic regions ( amino acids 52-59, 79-88 and 105-113) and one strongly hydrophilic region located between amino acids 72-79. |
Subcellular location: | NA |
Function: | One of the first observations of a circRNA behaving as a translational templates is the case of the single-stranded circular RNA genome of the hepatitis δ virus which is a satellite virus of the hepatitis B virus, where encapsulation of HDV with HBV virions results in the production of a single viral protein of 122 amino acids, in a non-canonical manner. |
Title of paper: | The hepatitis delta virus possesses a circular RNA |
PMID: | 2429192 |
Year of publication: | 1986 |